葛根素治疗52例冠心病心绞痛疗效观察

Clinical Effects of Puerarin in the Treatment of 52 Patients with Angina Pectoris

目的 :探讨冠心病心绞痛药物治疗的效果。方法 :将 10 4例冠心病心绞痛患者随机分成两组 :A组选用葛根素注射液 5 0 0 mg加入 5 %葡萄糖 5 0 0 ml静脉滴注治疗 ;B组采用镁 -极化液 5 0 0 ml静脉滴注 ,1次 /d,14d为 1个观察疗程。结果 :缓解心绞痛症状 ,A组总有效率达 84.6 % ,与 B组总有效率 42 .3%相比较有非常显著差异 ( P<0 .0 1) ;心肌缺血改善后心电图评定 ,A组总有效率 6 9.2 3% ,与 B组总有效率 34.6 %比较 ,P<0 .0 5。结论 :葛根素治疗冠心病心绞痛疗效肯定 ,毒副作用少 。

Objective: To evaluate the therapeutic effect of puerarin in treatment of angina pectoris. Methods: 104 patients suffered from coronary heart disease with angina pectoris were randomly divided into the puerarin treatment group (A group) and the magnesium polarized liquid treatment group (B group). A group was treated with puerarin iv drip of 500mg mixed 500mL of 5% glucose q.d. for 14 days. B group was treated with 500mL magnesium polarized liquid iv drip q.d. for 14 days. Results: After treatment, the total efficient rate of remittence angina pectoris in A group was 84.6%, while in B group was 42.3% (P<0.01 ). The total efficient rate of improvement ECG of the ischemic myocardium in A group was 69.23%, while in B group was 34.6% (P<0.05). Conclusion: Puerarin is an effective and safe antiangina drug and suitable for patients with angina pectoris.