中西药联合治疗急性期狼疮性肾炎79例

Integrated Chinese and Western Medicine in Treating 79 Cases of Acute Stage of Lupus Nephritis

目的:观察中西药联合治疗急性期狼疮性肾炎的临床疗效。方法:对采用不同治疗方法的2组病例进行回顾性对比分析,治疗B组采取抗感染、降血压或血液透析等西医对症治疗,治疗A组在治疗B组基础上加活血化瘀汤中医辨证治疗,比较2组治疗3个月后尿蛋白量、尿红细胞、血浆蛋白及舒张压变化情况。结果:治疗前后2组尿蛋白量、尿红细胞、血浆蛋白及舒张压组内比较均有统计学意义(P<0.05);治疗A组治疗后的上述指标优于治疗B组;治疗A组治疗后总有效率更优(P<0.05)。结论:中西药联合治疗急性期狼疮性肾炎疗效显著,可将其推广于临床。

Objective： To observe clinical effect of integrated Chinese and Western medicine in treating acute lupus nephritis. Methods： Retrospective comparative analysis was conducted on two different groups. Group B used western medicine treatment including anti-infection,lowering blood pressure or blood dialysis. Apart from receiving the same treatment as group B,patients in group A received additional Chinese medicine treatment of Huoxue Huayu Decoction. The changes of amount of urinary protein,red blood cells and plasma proteins in urine as well as diastolic blood pressure in the two groups were compared. Results： There were significant differences on amount of urinary protein,red blood cells and plasma proteins in urine as well as diastolic blood pressure before and after treatment in both groups （P0.05） . There were better results on the above indexes in group A; the total effective rate was higher in group A （P0.05） . Conclusion： There is significant therapeutic effect of integrated Chinese and Western medicine in treating acute lupus nephritis, and it is worth generalizing.