中医辨证施治结合化疗对晚期胃癌的临床疗效分析

Analysis on Clinical Effect of Syndrome Differentiation of Traditional Chinese Medicine Combined with Chemotherapy in Treating Late Gastric Cancer

目的:探讨晚期胃癌采用中医辨证施治结合化疗的临床疗效。方法:选取2006年1月至2012年8月我院收治的晚期胃癌患者共100例,随机分为治疗组和对照组,其中治疗组患者采用中医辨证施治结合化疗药物,而对照组患者仅采用化疗药物治疗。结果:治疗组与对照组患者的有效率差异有统计学意义(42.00%VS34.00%,P<0.05);治疗后治疗组患者的Karnofsky评分明显高于对照组(P<0.05);治疗后治疗组患者的半年、1年生存率分别为76.00%、44.00%,均明显高于对照组患者的半年、1年生存率(36.00%、10.00%),差异有统计学意义(P<0.05)。结论:晚期胃癌患者采用中医辨证施治结合化疗药物治疗,可显著提高其对化疗的耐受能力,增加生存时间及提高生活质量,故值得在临床上推广应用。

Objective： To explore the clinic effect of syndrome differentiation of traditional Chinese Medicine combined with chemotherapy in treating late gastric cancer. Methods： One hundred patients suffered from late gastric cancer admitted to our hospital from Jan 2006 to Aug 2012 were randomly divided into treatment group and control group. Patients in the treatment group were given syndrome differen-tiation of traditional Chinese Medicine combined with chemotherapy while the control group only applied chemotherapy. Results： There were significant difference in the total effective rate between the treatment group and control group （42.00% compared with 34.00% ,P0.05） ; the Karnofsky score in treatment group was significantly higher than that in control group（P0.05） ; the survival rates of patients 6 month and one year after treatment in treatment group were respectively 76. 00% and 44. 00% ,which were both higher and significantly different compared with the control group （ 36% and 10% ） . Conclusion： Syndrome differentiation of traditional Chinese Medicine combined with chemotherapy treating late gastric cancer could significantly strengthen the tolerance of chemotherapy,increase survival period,improve the quality of life,so it is worth generalizing clinically.