FIB、PLT、PT水平与缺血性进展型卒中关系的研究

Study on the relationship of levels of FIB,PLT,PT and progressive ischemic stroke

目的探讨缺血性卒中的进展与纤维蛋白原(FIB)、血小板(PLT)、凝血酶原时间(PT)的关系。方法观察缺血性卒中住院患者计427例。依据本研究确定的缺血性进展型卒中标准,确定脑卒中患者进展型136例为进展组,非进展型脑卒中患者291例为对照组。统计记录入院时患者FIB、PLT、PT水平,观察结束后对数据进行统计学处理。结果缺血性卒中两组间FIB水平差异无统计学意义(P>0.05);PLT、PT水平差异均有高度统计学意义(P<0.01)。结论缺血性卒中的进展与FIB无明显关系,与PLT、PT水平关系密切。患者发病时的PLT、PT水平是缺血性卒中进展的重要危险因素。

Objective To investigate the relationship of the progress of stroke and the levels of fibrinogen （FIB）, platelet （PLT）, prothrombin time（PT）. Methods Analyzed the data of 427 cases of hospitalized patients with isehemic stroke. Based on the diagnostic criteria of progressive stroke, 136 cases of patients belonged to the progress group, while 291 cases of patients belonged to the control group,recorded the levels of FIB, PLTand PT on admission, statisti- cal processed these data after the observation. Results The FIB level between the two groups was not significant differ- ent （P 〉 0.05）;and the levels of PLT, PT between the two groups were significant different （P 〈 0.01）. Conclusion There are no obvious relationship between FIB level and the progress of stroke,but there are close relationship between levels of PLT, PT and the progress of ischemic stroke.The levels of PLT and PT are important risk factors for ischemic stroke in progress while patient is sick.