普米克令舒联合万化吸入治疗毛细支气管炎的疗效观察

Efficacy of pulmicort joint ventolin inhalation in treatment of bronchiolitis

目的观察和分析治疗毛细支气管炎的两种药物普米克令舒联合万托林雾化吸入治疗的疗效及安全性。方法 2011年1月～2012年1月在我科住院确诊的毛细支气管炎患儿70例作为观察对象,全部患儿分为观察组38例和对照组32例,两组均予吸氧、抗病毒,必要时加用抗生素,静脉激素及氨茶碱平喘,合并心衰患者给予强心、利尿、扩血管等对症支持治疗。治疗组在此基础上停用静脉激素改用普米克令舒加万托林吸入治疗。用法:普米克令舒≥1岁每次2 mL,<1岁每次1 mL;万托林雾化吸入治疗每次0.5 mL,每次5～10 min,疗程5～7 d。比较两组的疗效及比两组患儿的主要症状、体征消失时间。结果治疗组的总有效率明显高于对照组,差异有统计学意义(P<0.05),治疗组患儿喘憋消失时间、喘鸣音消失时间、咳嗽消失时间均明显短于对照组,差异有统计学意义(P<0.05)。结论普米克令舒联合万托林雾化吸入治疗毛细支气管炎疗效显著,安全性好,值得推广和应用。

Objective To explore the pulmicort combined ventolin inhalation in treatment of bronchiolitis efficacy and safety. Methods Seventy cases diagnosed in infants with bronchiolitis hospitalized in our department from January 2011 to January 2012 as the observed objects. All patients were divided into the observation group with 38 cases and the control group with 32 cases, two groups were all given all oxygen, anti-virus, and when necessary, the use of antibiotics, intravenous hormone and aminophylline and asthma, complicated by heart failure patients given strong heart, diuretic, vasodilator symptomatic and supportive treatment. On this basis, the treatment group intravenous hormone was disabled switch to pulmicort shugar ventolin inhalation therapy. Usage： Pulmicort Respules, ≥ 1 year of age per 2 mL of 1-year-old every time 1 mL; Ventolin each 0.5mL atomization inhalation therapy, every 5 to 10 minutes of treatment 5 to 7 days. The main symptoms of the two groups were compared the efficacy and contrast the two groups of children, the signs disappeared were compared. Results The total rate of treatment group was significantly higher than that in control group, the difference was significant, treatment group children with wheezing disappeared, wheezing disappeared time, the cough disappeared were significantly shorter than the control group, the difference was significant. Conclusion The effect of pulmicort respules united ventolin atomization inhalation therapy bronchiolitis is exact and it is, worthy of promotion and application.