住院冠心病患者伴发抑郁障碍状况的临床探讨

Discussion on the influence factors on hospitalized patients with coronary artery disease and depressive disorder

目的探讨住院冠心病患者伴发抑郁障碍状况及影响因素。方法选择我院2011年4月～2012年12月心血管科收治的冠心病患者400例,采用抑郁自评量表(SDS)对所有患者进行抑郁障碍程度评定,并统计抑郁患者抑郁程度以及与性病关系,调查分析抑郁患者临床资料,总结冠心病伴发抑郁障碍影响因素,将抑郁障碍患者定义为实验组,随机抽取同等数量非抑郁冠心病患者作为对照组,调查两组患者功能失调性态度总分,进行认知评价。结果 400例患者中无抑郁障碍患者为335例,抑郁障碍65例,占16.25%,65例抑郁患者中,轻度抑郁23例,中度抑郁35例,重度抑郁7例,各抑郁程度男女发生例数对比差异显著(P<0.05),对65例冠心病伴发抑郁患者临床资料进行调查分析,多因素Logistic回归分析结果显示,住院冠心病患者抑郁障碍与个人因素、经济因素、慢性病因素、突发事件因素、不良嗜好因素关系密切。实验组与对照组功能失调性态度总分对比,差异有统计学意义(P<0.05)。结论影响冠心病患者抑郁障碍因素较多,其中性别为其中明显因素之一,其次为个人因素、经济因素、慢性病因素、突发事件因素、不良嗜好因素。冠心病患者认知评价水平也是影响其抑郁障碍的重要因素。

Objective To investigate the factors of influence on hospitalized patients with coronary artery disease and depressive disorder. Methods Four hundred patients with coronary heart disease in our hospital from April 2011 to December 2012 were analyzed in cardiovascular department, Self-Rating Depression Scale（SDS） was performed on all patients for evaluation of depression degree, we counted the relationship between the depressive degree and venereal disease, investigated and analyzed the patients＇ data, summaried the influencing factor of patients with coronary heart disease and depressive disorder. The depressive patients were defined as experimental group, the same number pa- tients of non-depressed disease as control group, we investigated two groups＇ dysfunctional attitude score and made cognitive evaluation. Results In 400 patients,non-depressive disorder patients,335 cases ;depressive disorder pa- tients,65 cases,which accounts for 16.25% in the total cases.In 65 cases of depression patients, 23 cases with mild depression, 35 cases with moderate depression,7 cases with severe depression. The P of gender comparative incidence in degree of depression （P 〈 0.05）. Analyzed on 65 cases of coronary heart disease, the influencing factors of depressive disorder in patients with coronary heart disease summed as personal factors, economic factors, factors of chronic dis- ease, sudden events, bad habits factors. The P of comparison between experimental group and the control group in dys- functional attitudes scores （P 〈 0.05）, it had obvious statistical significance. Conclusion There are many factors which in- fluence on the coronary heart disease patients with depression, in which gender is one obvious factors,the other factors include personal factors, economic factors, factors of chronic disease, sudden events and bad habits factors. The self~ cognitive evaluation in patients with coronary heart disease is also Important factors which influence depressive degree.