针灸对颈动脉粥样硬化形态和血流动力学影响的临床研究

Clinical Resaerch on Influence of Acupuncture on Morphous and Hemodynamics of Carotid Atherosclerosis

目的:观察针灸对颈动脉粥样硬化形态和血流动力学的影响。方法:以颈动脉粥样硬化患者为研究对象,将60例患者随机分为两组,治疗组采用穴位针灸结合立普妥(阿托伐他汀钙片)口服,对照组采用立普妥口服治疗,观察两组患者的颈动脉血流动力学指标的变化、斑块的消退情况以及TC、TG等相应生化指标的变化情况。结果:治疗后两组患者的颈动脉斑块形态改变和血流动力学数值与治疗前相比,差异均具有显著性意义(P<0.05),治疗组在治疗后的斑块形态良性改变以及PSV(峰值流速)、EDV(舒张末期流速)、PI(搏动指数)数值明显高于对照组,RI(阻力指数)数值明显低于对照组(P<0.05)。结论:针灸对颈动脉粥样硬化斑块中的扁平斑和软斑有消退作用,能够明显减小此类斑块的厚度和面积,是一种安全、有效、经济、便捷且值得临床推广的新方法。

Objective： To observe the influence of acupuncture to the carotid atherosclerosis with the variation on the morphous and hemodynamics. Methods： 60 cases were selected and randomly divided into two categories：the treatment group and the control group. The former was dealed with acupuncture and Lipitor（Atorvastatin） for oral use while the lat- ter took Lipitor orally. The diversity of the carotid atherosclerosis hemodynamics＇s index, the regression condition of the plaque and the variation of the homologus biochemistry targets such as serum total cholesterol and triglyceride were ob- served in two groups. Results： The morphous change of carotid plaque and hemodynamics numerus of two groups were both more differential after treatment（ P 〈 0. 05）. And that of the treatment group was much higher than the control group on the aspects of the optimal change on morphous plaque and the fig. on PSV （peak value）, EDV （diastasis flow rate） and PI（ pulsatility index） while RI（ resistant index） was much lower after acupuncture（P 〈 0.05 ）. Conclusion ： Acupuncture has a good effect on regression of the applanate plaque and blet of the carotid atherosclerosis,it can obviously diminish the thickness and area of this kind of plaque. If a new therapy which is safe, effective,ecominic,conveninent and worthy of clinical generalization.