七情因素与多囊卵巢综合征中医证型及性激素水平相关性研究

Correlated Study on TCM syndrome and Sex Hormone Levels of Polyeystie Ovary Syndrome and Emotional Factors

目的:探讨七情因素与多囊卵巢综合征(PCOS)中医证型及性激素水平的相关性,为PCOS的心身同治提供依据。方法:运用"七情背景量表"对首次确诊的100例PCOS患者(在告知诊断前)进行情志状态测评,并进行中医证型诊断及血清LH、FSH、E2、T、PRL检测。结果:PCOS患者中51例为肝郁型,占51%;肾虚型28例,占28%;痰湿型12例,占12%;瘀血型9例,占9%。肝郁证组"怒"的评分显著高于肾虚证组和瘀血证组(P<0.05),"悲"、"恐"与肝郁证呈负相关(P<0.05,P<0.01),"怒"与PRL呈正相关(P<0.05)。结论:"怒"是PCOS重要的致病因素和影响因素,肝郁证是PCOS最基本的病理变化,可以运用"以情胜情"的心理学方法防治PCOS。

Objective：Through exploring whether TCM syndromes or sex hormone levels of the women suffering from polycystic ovarian syndrome（PCOS） correlate with seven emotional factors,so as to provide basis for treatment of PCOS. Methods ：The emotional statements of 100 cases of first diagnosed PCOS patients（ before telling their diagnosis） were in- vestigated by background scale of seven emotional factors, then TCM syndrome type and the levels of LH, FSH, E2 , T and PRL in serum were tested. Results：51 cases of PCOS were liver depression type, accounting for 51% ; 28 cases were kidney deficiency type, accounting for 28% ; 12 cases were phlegm - damp type, accounting for 12% ; 9 cases were blood stasis type, accounting for 9%. The anger scores of liver depression type were significantly higher than that of kid- ney deficiency type and blood stasis type （ P 〈 0.05 ）, the sad and fear scores were negatively correlated with liver de-pression type （P 〈 0. 05, P 〈0. 01 ）, the anger scores and PRL levels were positively related （ P 〈 0. 05 ）. Conclusion ： The anger was an important pathogenic factor and PCOS influence factor, liver depression was the most basic pathological change of PCOS, and all the results pointed out a psychotherapy of TCM named controlling an excessive emotion by anoth-er may be an effective method to deal with PCOS.