曲安奈德治疗糖尿病黄斑囊样水肿的临床分析

The Clinical Analysis of Triamcinolone Acetonide for Cystoid Macular Edema in Diabetic

目的探讨曲安奈德治疗糖尿病黄斑囊样水肿的临床疗效。方法选取2011年8月至2013年1月我院收治的60例糖尿病黄斑囊样水肿患者,共84眼。所有患者行球后注射曲安奈德后测量评价患者治疗1周后视力恢复情况;将治疗后1、2、3个月后的视力、眼底血管造影和黄斑中心凹视网膜厚度与治疗前比较,随访患者并发症发生情况。结果治疗1周后,全部患者视力提高率为92.86%(78/84眼);治疗1、2、3个月后患者眼底血管造影黄斑部荧光渗漏面积明显缩小或消失,视力和黄斑中心凹视网膜厚度均优于治疗前,差异显著,具有统计学意义(P<0.05);所有患者随访3个月期间,并发症发生率为0。结论球后注射曲安奈德治疗糖尿病黄斑囊样水肿具有良好效果,不良反应少的优点,值得在临床推广应用。

Objective To investigate the triamcinolone acetonide for diabetic macular edema clinical efficacy. Methods August 2011-2013 in January in our hospital 60 cases of cystoid macular edema in patients with diabetes, a total of 84. All patients underwent retrobulbar injection of triameinolone acetonide in patients after treatment, measurement and evaluation of visual acuity after 1 week of treatment situations; would 1,2,3 months after treatment visual,acuity maeular f[uoreseein leakage area and central macular thickness than before treatment, the incidence of complications in patients with follow- up. Results 1 week after treatment, visual acuity improved in all patients was 92.86% （78/84）; 1,2,3 months after treatment maeular fluorescein leakage area was significantly reduced or disappeared, visual acuity and central maeular thickness were better than before treatment, the difference was significant, with statistical significance （P〈0.05）; All patients were followed three month period, the complication rate was 0. Conclusion Triamcinolone aeetonide treatment of diabetic macular edema with better treatment, the advantage of fewer adverse reactions, it is worthy of clinical application.