PCT与hs-CRP在新生儿感染早期诊断的临床研究

PCT and hs-CRP in the early diagnosis of neonatal infection

目的比较在新生儿感染中降钙素原(PCT)、超敏C反应蛋白(hs-CRP)在早期诊断中的临床价值。方法选取新生儿感染129例,按感染病原分为细菌感染组(细菌组)、支原体/衣原体感染组(支/衣原体组)、病毒感染组(病毒组),健康新生儿30例为对照组,对比四组患者间临床资料差异性。结果 PCT、hs-CRP在细菌组水平最高,支/衣原体组次之,病毒组无明显改变。结论 PCT对新生儿感染诊断有早期诊断意义,将PCT、hs-CRP联合诊断,敏感度、特异度较高。

Objective To compare the in neonatal infection of PCT,hs-CRP in the early diagnosis of clinical research.Method Select 129 cases of neonatal infection,according to the divided into bacteria group、mycoplasma/Chlamydia group、viral group,30 healthy neonates were selected as control group,compared four groups of patients with clinical data were.Result PCT、hs-CRP,the highest level in bacterial group,mycoplasma /Chlamydia group,virus group had no obvious change.PCT、hs-CRP combined with high diagnostic sensitivity and specificity.Conclusion PCT diagnosis of neonatal infection has the significance of early diagnosis of PCT,hs-CRP,diagnosis,sensitivity,specificity of the most satisfactory.