综合医院住院病人HIV及梅毒感染状况

HIV and syphilis screening among hospitalized patients in the general hospital

目的探讨住院病人艾滋病病毒(HIV)及梅毒感染状况。方法对广西民族医院2007年1月-2011年12月的住院病人,采用酶联免疫吸附试验(ELISA)进行HIV、梅毒抗体筛查,并对HIV抗体阳性反应病例进一步做蛋白免疫印迹试验(WB)确认;梅毒-ELISA阳性者采用甲苯胺红不加热血清试验(TRUST)检测抗体滴度。结果 31 562例住院病人中,HIV检出率为1.36%(429例),其中20～40岁年龄段占79.95%。HIV感染者分布于医院的20个科室,内科占65.27%,外科占29.60%,其他科室占5.13%。梅毒抗体检出率为1.29%,其中潜伏梅毒占58.62%,>50岁年龄段占52.09%;290例梅毒病人广泛分布于全院各个科室。结论综合医院的HIV和梅毒病人增加,应加强对住院病人的HIV、梅毒抗体检测,及早发现HIV/感染者和梅毒病人及潜伏梅毒,以便确诊并进行及时治疗,防止进一步传播。

Objective To investigate the infection status of HIV and syphilis in hospitalized patients in the general hospital.Methods Retrospective study was conducted between January 2007 and December 2011 to analyze the HIV and syphilis antibodies test results obtained by using enzyme-linked immunosorbent assay（ELISA） and Western blotting（WB）.Antibody titer of the TP-ELISA positives was tested with tolulized red unheated serum test assays（TRUST）.Results In 31 562 hospitalized patients,the positive rate for HIV antibody was 1.36%（429）,and that in the 20-40 years group accounted for 79.95%.HIV patients distributed in 20 different departments in the hospital,of which 65.27% were in the internal medicine departments,29.60% were in the surgical departments,and 5.13% were in other departments.For syphilis antibody screening test,the positive rate was 1.29%,that in patients with latent syphilis accounted for 58.62%;and that in the patients aged above 50 accounted for 52.09%.A total of 290 syphilis antibody positive patients were from nearly all clinical departments in the hospital.Conclusion HIV and syphilis infections are increasing in the general hospital.Thus,screening tests for HIV and syphilis should be carried out as a routine practice in hospitalized patients to discover patients in the latent period and to provide timely treatment for preventing further spread.