Lewis酸离子液体催化合成TCPP

Synthesis of Tris(β-chloropropyl)Phosphate Ester Catalyzed by Lewis Acid Ionic Liqiuds

以三氯氧磷和环氧丙烷为原料,在离子液体Et3NHCl-x[AlCl3]催化作用下合成了磷酸三(β-氯丙基)酯(TCPP).确定最佳工艺条件为:n(POCl3)∶n(C3H6O)=1∶3.3,反应温度60～65℃,催化剂用量0.05 g,环氧丙烷的滴加时间约为3 h,产率达98.5%.此工艺有催化剂用量少,产率高,成本低等优点.

Tris（β-chloroprupy] ）phosphate （TCPP）was synthesized with phosphorus oxychloride and propylene epoxside as raw materials, using ionic liquids Et3 NHCI-x [ AlCl3 ] made by ourselves as catalyst for the reaction. It was shown that the proper reaction conditions were： the molar ratio of propylene epoxide to phosphorus oxychloride was 1：3.3, reaction temperature was 60℃ - 65℃. The mass of catalyst was 0.03% of phosphorus oxychloride, and dropwise time of propylene oxide was 3 h. The yield of the product TCPP reached 98.5%. This technology has several advantages ,such as small amount of catalyst, high yield and low cost.