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新型含寡聚乙二醇链的苄醚树状化合物的合成及其溶液性质 被引量：2

Synthesis and Solution Properties of Novel Benzyl Ether Dendrimer with Oligoethyleneoxy Chains
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摘要 以5-氨基间苯二酚为起始原料,设计并合成了2个新型的含寡聚乙二醇链的苄醚树状化合物———3,5-二-{2-[2-(2-甲氧基-乙氧基)-乙氧基]-乙氧基}-苯氨基甲酸叔丁酯(4)和3,5-二-{3,5-二-{2-[2-(2-甲氧基-乙氧基)-乙氧基]-乙氧基}-苄氧基}-苯氨基甲酸叔丁酯(7),其结构经1H NMR,13C NMR,IR和ESI-HR-MS表征。利用UV-vis光谱研究了4和7的溶液性质,结果表明4和7有热敏感性,其浊点随浓度的增加而降低。 Two novel thermosensitive benzyl ether dendrimer with oligoethyleneoxy chains,tert-butyl 3,5-bis{2-[2-（2-methoxyethoxy）ethoxy]ethoxy}phenylcarbamate（4） and tert-butyl 3,5-bis{3,5-bis{2-[2-（2-methoxyethoxy）ethoxy]ethoxy}benzyloxy}phenylcarbamate（7）,were desinged and synthesized from 5-aminoresorcinol.The structures were characterized by 1H NMR,13C NMR,IR and ESI-HR-MS.The solution properties of 4 and 7 were investigated by UV-vis.The results showed that 4 and 7 exhibited thermosensitivity,and the turbidity decreased with increasing concentrations.
作者 林志忠 刘敬欣 李良春 王启卫 朱槿 邓金根
机构地区 中国科学院成都有机化学研究所 中国科学院大学 四川大学华西药学院 西南科技大学生命科学与工程学院
出处 《合成化学》 CAS CSCD 北大核心 2013年第4期432-435,439,共5页 Chinese Journal of Synthetic Chemistry
基金 国家自然科学基金资助项目(91027022 21002099 20428202) 国家重点基础研究发展计划(973)项目(2010CB833300)
关键词 树状化合物 寡聚乙二醇 苄醚 热敏感性 合成 dendron oligoethyleneoxy benzyl ether thermosensitive synthesis
分类号 O625.32 [理学—有机化学]
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参考文献17

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同被引文献16

  • 1姜静,陈传福,习复,刘宏伟,赵优良.Synthesis and characterization of dendronized poly(methylsiloxane) with appendent Fréchet-type dendrons[J].Science China Chemistry,2002,45(6):633-639. 被引量：1
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  • 10Li W,Zhang A,Chen Y,et al. Low toxic,thermoresponsivedendrimers based on oligoethylene glycols with sharp andfully reversible phase transitions [J]. Chem Commun,2008,(45):5 948-5 950.

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合成化学
2013年 第4期

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