婴幼儿血管瘤非手术治疗方法的研究进展

Strategies of non-operative treatment for managing infantile hemangiomas

尽管有些婴幼儿血管瘤可自然衰退和治愈的,但对较严重的血管瘤,可能威胁生命的如气道或视神经处占位的和导致局部组织严重破坏影响外观的婴幼儿血管瘤,需要进行早期干预治疗。随着对血管瘤的非手术治疗方法的分子作用机制、副作用和疗效认识的不断加深,治疗血管瘤的方式也变的多种多样。该文回顾性综述了现有文献的非手术治疗婴幼儿血管瘤的方法,包括这些方法的疗效、副作用及使用剂量等,对婴幼儿血管瘤治疗有一定的指导作用。

The majority of infantile hemangiomas（IHs） can be treated expectantly and allowed to involute spontaneously.Those that are life threatening,cause obstruction to the airway or visual axis,or cause distortion or destruction of local tissues require early intervention.With the advent of an improved understanding of the mechanism of action,complications and effects of the various treatments,available treatment options have expanded from the traditional ways.This article reviews the current literature on the treatment of IHs with steroids,interferon,propranolol,vincristine,bleomycin and laser,and effectiveness,side effects and dosage are discussed.Therefore,this article can provide a comprehensive understanding to clinicians.