期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

散发性乳腺癌患者BRCA1基因突变的分析 被引量：2

下载PDF
导出
摘要 乳腺癌是严重危害女性健康的恶性肿瘤之一，近年来，其发病率在我国逐渐上升并呈年轻化趋势。大量研究已经证实该疾病与雌激素、多种癌基因、抑癌基因相关。
作者 张亚芬 王江芬 高润芳
机构地区 山西省人民医院乳腺科
出处 《中国药物与临床》 CAS 2013年第8期1010-1012,共3页 Chinese Remedies & Clinics
基金 山西省卫生厅科技攻关项目(200907)
关键词 BRCA1基因突变 乳腺癌患者 散发性 抑癌基因 年轻化趋势 恶性肿瘤 女性健康 发病率
分类号 R737.9 [医药卫生—肿瘤]
  • 相关文献

参考文献13

  • 1Swisher EM,Sakai W,Karlan BY,et al. Secondary BRCA1 muta-tions in BRCA1-mutate ovarian carcinomas with platinum resis-tance. Cancer Res, 2008,68 : 2581-2586.
  • 2Miki Y,Swensen J,Shattuck ED,et al. A strong candidate for thebreast and ovarian cancer susceptibility gene BRCA1. Science,1994,266(5182):66-70.
  • 3Levy-Lahad E,Friedman E. Cancer risks among BRCA1 andBRCA2 mutation carriers. Br J Cancer,2007,96( 1) : 11-15.
  • 4Gayther AS,Harrington P,Russell P,et al. Rapid detection of re-gionally clustered germ-line BRCA1 mutations by multiplex het-eroduplex analysis. Am J Hum Genet, 1996,58(3) :451-456.
  • 5Radice P. Mutations of BRCA genes in hereditary breast and o-varian cancer. Exp Clin Cancer Res,2002,21(3) :9-12.
  • 6Palma M,Ristori E,Ricevuto E,et al. BRCA1 and BRCA2: thegenetic testing and the current management options for mutationcarriers. Crit Rev Oncol Hematol, 2006,57 ; 1 -23.
  • 7Fitz-Gerald MG,Mac-Donald DJ,Krainer M,et al. Germ-lineBRCA1 mutations in Jenish and non-Jenish women with early-onset breast cancer. New Engl J Med, 1996,334(3): 143-149.
  • 8Phelan CM,Kwan E,Jack E,et al. A low frequency of non-founder BRCA1 mutations in Ashkenazi Jewish breast-ovariancancer families. Hum Mutat,2002,20(5) :352-357.
  • 9赖春宁,江泽飞,宋三泰,王建安,黎燕,沈倍奋.38例散发乳腺癌患者BRCA1基因突变检测[J].癌症,1999,18(4):389-391. 被引量：10
  • 10王旭芬,丰美芳,杨吉成.50例散发性乳腺癌患者BRCA1基因的检测[J].苏州大学学报（医学版）,2004,24(1):91-92. 被引量：2

二级参考文献29

  • 1李士谔.细胞分化在致癌和抑癌中的作用（续）[J].中国医学科学院学报,1994,16(1):73-77. 被引量：9
  • 2Newman B Mu H 等.Frequency of breast cancer attributable to BRCA1 in a population-based series of American women[J].美国医学会杂志：中文版,1999,18(2):69-73.
  • 3[1]Hall JM, Lee MK, Newman B, et al. Linkage of early-onset familial breast cancer to chromosome 17q21 [J]. Science,1990,250(4988):1684-1689.
  • 4[2]Wooster R, Mangion J, Eeles R, et al. Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13[J]. Science,1994,265(5181):2088-2090.
  • 5[3]Szabo CI, King MC. Population genetics of BRCA1 and BRCA2[J]. Am J Hum Genet,1997,60(5):1013-1020.
  • 6[4]Krainer M, Silva-Arrieta S, Fitz-Gerald MG, et al. Differential contributions of BRCA1 and BRCA2 to early-onset breast cancer[J]. N Engl J Med,1997,336(20):1416-1421.
  • 7[5]Katagiri T, Kasumi F, Yoshimoto M, et al. High proportion of missense mutations of the BRCA1 and BRCA2 genes in Japanese breast cancer families[J].J Hum Genet,1998,43(1):42-48.
  • 8[6]Katagiri T, Emi M, Ito I, et al. Mutations in the BRCA1 gene in Japanese breast cancer patients[J]. Hum Mutat,1996,7(4):334-339.
  • 9[7]Inoue R, Ushijima T, Fukutomi T, et al. BRCA2 germline mutations in Japanese breast cancer families[J]. Int J Cancer,1997,74(2):199-204.
  • 10[8]Sng JH, Chang J, Feroze F, et al. The prevalence of BRCA1 mutations in Chinese patients with early onset breast cancer and affected relatives[J]. Br J Cancer,2000,82(3):538-542.

共引文献17

同被引文献8

引证文献2

二级引证文献5

中国药物与临床
2013年 第8期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部