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血管紧张素Ⅱ对胰岛β细胞的影响 被引量:2

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摘要 2型糖尿病(type 2 diabetes mellitus,T2DM)的发病率日益增高,其各种并发症严重危害着人们的生活质量和生命安全,因此成为医学界关注的重要问题之一。目前虽T2DM的发病机制尚未完全澄清,但研究表明T2DM是以胰岛素抵抗和胰岛细胞功能衰竭为主要特征,
出处 《中国药物与临床》 CAS 2013年第8期1012-1014,共3页 Chinese Remedies & Clinics
基金 山西省卫生厅科技攻关项目(201201074)
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  • 1Hasegawa H, Komuro I. The progress of the study of RAAS. Nip-pon Rinsho, 2009,67(4) ; 655-661.
  • 2Guillausseau PJ,Meas T, Virally M,et al. (2008) Abnormalitiesin insulin secretion in type2 diabetes mellitus. Diabetes Metab,34 Suppl 2:S43-48.
  • 3Imanishi T,Hano T,Nishio I. AngiotensinII accelerates edothe-lial progenitor cells senescence through induction of oxidativestress. J Hypertens, 2005,23 (1): 97-104.
  • 4Shan HY,Bai XJ,Chen XM. Apoptosis is involved in the senes-cence of endothelial cells induced by angiotensin II. Cell BiolInt,2008,32(2):264-270.
  • 5De Angelis N,Fiordaliso F,Latini R,et al. Appraisal of the roleof angiotensin II and aldosterone in ventricular myocyte apoptosisin adult Normo- tensive rat. J Mol Cell Cardiol,2002,34( 12):1655-1665.
  • 6Leung PS,Carlsson PO. Pancreatic islet rennin-angiotensin sys-tem :its novel roles in islet function and in diabetes mellitus.Pancreas, 2005,30(4) : 293-298.
  • 7Kampf C,Lau T,01sson R,et al. Angiotensin D Type 1 receptorinhibition markedly improves the blood perfusion, oxygen tensionand first phase of glucose-stimulated insulin secretion in revascu-larised syngeneic mouse islet grafts. Diabetologia,2005,48(6):1159-1167.
  • 8Robertson RP,Harmon J,Tran PO,et al. Glucose toxicity in be-ta2cells: type 2 diabetes, good radicals gone bad, and the glu-tathione connection. Diabetes,2003,52(3);581-587.
  • 9Kuhad A,Chopra K. Attenuation of diabetic nephropathy by to-cotrienol:involvement of NF-kB signaling pathway. Life Sci,2009,84(9-10):296-301.
  • 10Border WA,Noble NA. Transforming growth factor beta in tissuefibrosis. N Engl J Med, 1994,331(19) ; 128.

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