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缺氧诱导因子-1α和血管内皮生长因子在非小细胞肺癌中的表达及意义 被引量:4

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摘要 血管生成在肿瘤的发生、发展和转移中起重要作用。研究表明缺氧诱导因子(hypoxia induced factorl,HIF)-1在肿瘤缺氧环境中起着中枢纽带作用,对血红素加氧酶、葡萄糖转运蛋白、糖酵解酶、血管内皮生长因子(vascular endothelial growth factor,VEGF)、促红细胞生成素以及P53等细胞酶和蛋白起着调节作用,
出处 《中国药物与临床》 CAS 2013年第8期1023-1025,共3页 Chinese Remedies & Clinics
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参考文献8

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同被引文献38

  • 1胡毅,冯奉仪,程书钧,高燕宁,肖汀,刘又宁.PC细胞来源的致瘤生长因子在非小细胞肺癌患者血清中的表达与化疗敏感性相关分析[J].中华肿瘤杂志,2006,28(8):603-605. 被引量:3
  • 2何立丽,张伟京,苏航,徐东刚.Ang-2与VEGF的协同作用及其在抗肿瘤血管新生治疗中的应用[J].中国实验血液学杂志,2007,15(2):445-448. 被引量:12
  • 3李晓民,汪克明,刘婧,吴子建,周逸平,蔡荣林.大鼠心肌缺血再灌注模型的有效复制方法[J].中国心血管病研究,2007,5(6):463-464. 被引量:9
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