分析2型糖尿病患者糖尿病视网膜病变相关因素

Analysis of relevant factors in diabetic retinopathy of type-two diabetes mellitus

目的探讨2型糖尿病患者糖尿病视网膜病变(DR)发生发展的相关因素,以早期预防及指导临床治疗。方法对316例2型糖尿病患者根据其眼底情况分为无DR组和DR组,比较可能诱发DR的相关因素。结果 Logistic分析显示:病程、糖化血红蛋白、收缩压、胆固醇、甘油三脂、24小时尿白蛋白排泄率与DR有显著相关。结论病程、糖化血红蛋白、收缩压、胆固醇、甘油三脂、24小时尿白蛋白排泄率为DR发生的重要危险因素,应重视并针对其危险因素加以预防。

Objetive To prevent and treat early diabetic retinopathy （DR） by analyzing its relevant risk factors. Methods 316 cases with type 2 diabetes mellitus were divided into two groups： non diabetic retinopathy group（NDR group） and diabetic retinopathy group（DR group） Their correlated risk factors were analyzed. Results Logistic regression analysis revealed that course of disease, HbAlc, systolic blood pressure（SBP）, cholesterol（TC）, triglyceride（TG）, and 24 hour urinary protein excretion were associated with DR. Conclusion More attention should be paid to the risk factors to prevent DR occurrence.