青鱼“出血症”的病理形态学观察

Pathological Changes of Mylopharyngodon Piceus with Septicemia Disease

对具有典型出血症状的青鱼自然病例进行了病理形态学观察.镜检发现病鱼多个组织器官充血和出血,实质细胞出现变性、坏死及炎症细胞浸润的现象,尤其是肝、肾及肠道的组织损伤严重.肝间质充满大量炎性细胞,肝小叶中肝细胞排列紊乱,胞浆空泡化,大量肝细胞的脂肪变性,并出现大面积坏死;前肠杯状细胞数量降低,绝大部分绒毛上皮细胞呈现弥漫性坏死,整片地分离脱落,固有层水肿、细胞排列疏松;肾小球内皮细胞增生、肿胀,肾小管细胞严重空泡变性,间质充血、细胞水肿成团,集合小管空泡变性,形成花瓣状细胞;肌肉横纹肌不清楚,有水肿.

The histopathological examination for typical hemorrhagic symptomatic of natural cases in Mylopharyngodon piceus was made; hemorrhage and hyperaemia, degeneration and necrosis of the parenchyma cell, inflammatory cell infiltration were observed in many tissues and organs through microscopic observations, especially on the liver, kidney and intestinal tract. There were severely vacuolar degeneration of the liver cells and a large area of necrosis, the hepatic mesenchymes were filled with a large number of inflammatory cells.The number of goblet cell declines, and the vast majority of chorionic epithelium was presented diffusely necrosis and dropped,Lamina propria was edema and the cell was range loosen, glomerular endothelial cell was hyperplasia and swelling.Seriously vacuolar degeneration of renal tubular cells and the interstitial congestion and the cell edema form lumps.Vacuolars of collecting tubule degenerate to ＂flower＂ cells. The striated muscle was uncleared and edemaed.