毁损隔区对大鼠P_(3b)电位的影响

EFFECT OF P_(3b) POTENTIAL AFTER BILATERAL SEPTAL LESION IN RATS

目的 :探讨毁损隔区对大鼠P3b电位的影响。方法 :记录隔区、海马CA1区的P3b电位且同步记录相应脑区细胞放电 ,观察毁损隔区对海马CA1区P3b电位及细胞放电的影响。结果 :隔区损毁后 ,海马CA1区P3b电位及细胞放电基本同步减弱直至消失。结论

Objective: To discuss the changes of P 3b after septal lesion. Methods: P 3b potentials and cell electric discharge were recorded simultaneously inside cranio,septal and hippocampal CA1 region in rats. After septal lesions,the changes of P 3b and cell electric discharge in hippocampal CA1 region were observed. Results :After septal lesions, P 3b and cell electric discharge decreased gradually and disapeared eventually. Conclusion: Normal structure and function of septal are necessary to P 3b 's generation in hippocampal CA1 region.