成人急性白血病医院感染危险因素及对策

The Risk Factors and Countermeasures of Acute Leukemia Nosocomial Infection for Adult

目的:为了进一步研究导致成人急性白血病患者发生医院感染的危险因素,从而为临床实践提供借鉴和参考。方法:本文以本院2011年12月-2013年1月期间入院治疗的466例成人急性白血病患者为研究对象,针对患者的临床资料进行回顾性分析。结果:本次调查的成人急性白血病医院感染发生率为30.04%;大于或等于60岁患者的感染率(47.22%)显著地高于小于60岁的患者(15.20%);实施化疗患者的感染率(33.59%)显著地高于未实施化疗的患者(10.00%);住院时间大于30d患者的感染率(51.65%)显著地高于住院时间小于15d(6.12%)和15～30d(31.41%)的患者,差异均具有统计学意义(P<0.05)。结论:患者的年龄、实施化疗情况、住院时间是导致急性白血病医院感染的危险因素。

Objective：To further investigate the risk factors and countermeasures of acute leukemia nosocomial infection for adult and provide reference for clinical practice. Method：466 adult acute leukemia patients hospitalized in our hospital from December 2011 to January 2013 were chosen as the research object. The clinical data for patients was taken for retrospective analysis. Result：The survey of adult acute leukemia hospital infection rate was 30.04%;it was greater than or equal to infection rate（47.22%）of 60-year-old patients and was significantly higher than the less than 60-year-old patients（15.20%）. The infection rate of implementation of chemotherapy was 33.59%,it was significantly higher than the non-implementation chemotherapy patients（10.00%）. The infection rate for hospital stay greater than 30 d in patients was（51.65%）,significantly higher than the length of stay that less than 15 d（6.12%）and 15-30 d（31.41%）of the patients,the difference were statistically significant（P 0.05）.Conclusion：The patient’s age,the implementation of chemotherapy and the hospital stay are the risk factors that cause acute leukemia Hospital infection.