老年急性心肌梗死介入治疗疗效观察

The Curative Effect of the Interventional Therapy of Elderly Acute Myocardial Infarction

目的:探讨经皮冠状动脉介入治疗(PCI)老年急性心肌梗死的安全性以及临床疗效。方法:选取从2010年7月-2012年7月在本院进行经皮冠状动脉介入治疗的48例老年急性心肌梗死患者作为研究对象,为治疗组;随机原则选取同时期在本院进行内科药物保守治疗的48例老年急性心肌梗死患者为对照组。所有患者均经入院检查确诊为老年急性心肌梗死,两组患者在性别、年龄、病程及临床表现和辅助检查等一般情况方面比较无统计学意义(P>0.05)。观察两组治疗后的临床疗效、住院时间、病死率以及近期心脏不良事件的发生等情况。结果:治疗组和对照组的术后血管的再通率、院内病死率以及不良事件的发生率分别为97.92%、4.17%、6.25%和66.67%、12.5%、25.00%,各项两组比较差异均有统计学意义(P<0.05);治疗组和对照组的平均住院时间分别为(15.2±3.5)d、(20.4±5.2)d,两组住院时间比较差异具有统计学意义(P<0.05)。结论:经皮冠状动脉介入治疗(PCI)老年急性心肌梗死比传统内科药物溶栓治疗的临床疗效更显著。术后血管再通率高,住院时间短,近期患者发生的心脏不良事件少,安全性更高,值得临床推广应用。

Objective：To observe the curative effect effect of the percutaneous coronary intervention（PCI）of elderly acute myocardial infarction and medication safety.Method：Selected 48 cases from July 2010 to July 2012 in our hospital undergoing percutaneous coronary intervention in patients with acute myocardial infarction as research subjects,randomly selected the same period of conservative treatment in our hospital for medical drug for the treatment group;48 elderly patients with acute myocardial infarction as the control group.All patients diagnosed with acute myocardial infarction after admission examination,the two groups in gender,age,duration and clinical manifestations and laboratory examinations in general was not statistically significant（P 0.05）.Clinical efficacy,duration of hospitalization,mortality and incidence of the recent adverse cardiac events were observed after treatment.Results：The rate of postoperative blood vessel,hospital mortality and the incidence of adverse events in treatment group and control group were 97.92%,4.17%,6.25% and 66.67%,12.5%,25.00%,the two groups of comparisons difference was statistically significant（P 0.05）;the hospitalization time in treatment group and control group were（15.2±3.5）d and（20.4±5.2）d respectively,the difference was statistically significant between the groups（P 0.05）.Conclusion：It suggested that the percutaneous coronary intervention（PCI）in elderly acute myocardial infarction than traditional medicine drugs thrombolysis treatment the clinical curative effect of the more prominent.Postoperative vascular high rate,shorter hospitalization time,the recent adverse cardiac events in patients with less,higher security,worthy of clinical popularization and application.