和胃颗粒治疗痞满证临床研究

Clinical Research of Stomach -regulating Granules on Distention and Fullness

目的评价和胃颗粒治疗痞满(寒热错杂、虚中夹实证)的疗效和安全性。方法将符合纳入标准的患者90例分为和胃颗粒治疗组60例、胃苏颗粒对照组30例,治疗4周并停药4周后观察疗效。结果总有效率治疗组为91.67%优于对照组的76.67%;两组均未发现明显不良反应。结论和胃颗粒治疗痞满(寒热错杂、虚中夹实证)有良好的临床疗效,且无明显毒副作用。

Objective： To evaluate the effect and safety of stomach-regulating granules on distention and fullness with the syndrome of intermingled cold and heat and the syndrome of deficiency complicated with excess.Methods： According to the inclusion and exclusion criterion,90 cases were divided into the treatment group with the stomach-regulating granules and the control group with the Weisu Granule.After a four-week treatment and a four-week drug withdrawal,these effects were observed and compared in 2 groups.Results： The total effective rate in the treatment group were superior to that in the control group.There were no adverse reactions in 2 groups.Conclusion： Stomach-regulating granules has good clinical effects for distention and fullness of the syndrome of intermingled cold and the syndorm of heat and deficiency complicated with excess.