血压昼夜节律与左室肥厚关系的研究

The study on the relationship between blood pressure circadian rhythm and left ventricular hypertrophy

目的 探讨轻中度高血压患者左室肥厚与血压昼夜节律的关系。方法 对 91例轻中度高血压左室肥厚患者进行动态血压监测 (ABPM)监测 ,根据监测结果将其分为两组 :血压节律正常组 (A组 ) 35例 ,异常组 (B组 ) 5 6例 ,将这两组患者ABPM和左室肥厚的参数进行比较。结果 B组比A组有较高的 2 4hSBP、nSBP、nDBP、收缩压负荷以及明显的LVMI(P <0 .0 5 ,P <0 .0 1)。结论 轻中度高血压患者其异常血压昼夜节律与左室肥厚密切相关 。

Objective The purpose of the study is to explore the relationship between left ventricular hypertrophy (LVH) and abnormal blood pressure circadian rhythm in patients with mild to moderate essential hypertension. Methods 91 patients with mild to moderate essential hypertension and LVH were examined in ABPM.Based on the results,the subjects were divided into two groups:normal blood pressure circadian rhythm group(group A),35 cases and abnormal blood pressure circadian rhythm(group B),56 cases.The parameters of ABPM and LVH were given comparison in the two groups. Results 24 hSBP, nSBP,nDBP,systolic blood pressure load and LVMI in group B were significantly higher compared with those in group A respectively(P<0.05,P<0.01).Conclusion The study showed that there was a close relationship between LVH and abnormal blood pressure circadian rhythm in mild to moderate hypertensive patients,and ABPM examination has significantly clinical meaning.