摘要
【目的】了解我院注射剂药品不良反应(adverse drug reaction,ADR)发生的特点及一般规律,开展药物警戒,减少不良反应发生,为临床合理用药提供参考。【方法】汇总统计我院2012年上报的178例注射剂ADR,对患者情况、药品种类、注射方法、累及器官或系统及临床表现等进行统计、分析。【结果】178例ADR报告中涉及的药物品种共有70种,其中抗感染药类药物19种(27.14%),居引发ADR的品种数首位;ADR发生以大分子量药物、中药复方制剂、抗感染药最为常见;ADR累及器官或系统以皮肤及其附件最为常见。【结论】临床使用注射剂应关注药物的种类、适用人群、临床表现等,了解药品不良反应发生机制,加强ADR监测报告工作,确保药物治疗安全、有效。
[Objective]To investigate the characteristics and regulations of adverse drug reaction (ADR) in our hospital ,Development of pharmacovi,to reduce adverse reactions, Provide references for clinical rational drug use. [Methods]Summary statics in our hospital in 2012 178 cases of ADR injection.on the condition of patients,the kind of drugs,injection method,involved organs or systems and clinical manifestations such as statics,analysis. [Results] 178 cases of ADR involving a total of 70 kinds of drugs,the anti-infective in 19 (27.14%),in the firet initiator ADR;ADR occurred in large molecular weight,the compound preparation of traditional Chinese medicine, antibiotics are the most common; ADR mainly involved organs or systems to the skin and its appendages are the most common. [Conclusion] Clinical attention should be paid to the types of drugs,is suitable the crowd clinical manifestation,Understanding of adverse drug reaction mechanism,strengthen the ADR monitoring work,ensure the drug safety,effective.
出处
《武警后勤学院学报(医学版)》
CAS
2013年第7期616-618,共3页
Journal of Logistics University of PAP(Medical Sciences)
关键词
药物不良反应
注射剂
统计
分析
监测
Adverse drug reaction
Injection
Statics
Analysis
Monitoring