放射性核素胃食管显像检测新生儿胃排空和胃食管反流

The determination of neonatal gastric emptying and gastroesophageal reflux with radionuclide gastroesoph ageal scintigraphy

目的 采用放射性核素胃食管显像评价新生儿胃排空和胃食管反流情况。方法 77例处于疾病恢复期的新生儿患者 ,其中足月儿 46例、早产儿 31例。用胃食管显像测定 6 0min胃排空率 (GE6 0 % )和胃食管反流指数 (RI)。结果 所有患儿均未发现不良反应。早产儿的胃排空率 [(2 8 3± 7 7) % ]明显低于足月儿 [(4 9 2± 12 8) % ],P <0 0 0 1。胎龄与胃排空率间存在正相关关系。足月儿无症状反流率为 6 0 9% (2 8 46例 ) ,早产儿中高达 83 9% (2 6 31例 ) ,差异有显著性 (P <0 0 5 )。结论 胃食管显像检测新生儿胃排空和胃食管反流是可行的 ;早产儿的胃排空率低于足月儿 。

Objective Toevaluateneonatalgastricemptyingandgastroesophagealrefluxwithgastroe sophagealscintigraphy Methods Gastrointestinalmotilitywasexpressedasgastricemptyingrateat6 0minafter feeding (GE6 0 % )andrefluxindex (RI)on99Tcm DTPAgastroesophagealscintigraphy 77normalneonateswere enrolledinthisstudy Results GE6 0 %inpreterminfantswaslowerthanthatinfull termneonates (2 8 3%± 7 7%vs 49 2 %± 12 8% ) Gestationalagewaspositivelycorrelatedtogastricemptyingrate Asymptomatic gastroesophagealrefluxwas 6 0 9%in 46full termneonatesand 83 9%in 31preterminfants,P <0 0 5 Con clusions Gastroesophagealscintigraphycanbeusedtoexamineneonatalgastricemptyingandgastroesophageal reflux PreterminfantshavelowerGE6 0 %thanthatinfull termneonates Thereisaconsiderableincidenceof asymptomaticgastroesophagealrefluxinnormalneonates