摘要
目的对川牛膝的化学成分进行研究。方法反复采用大孔树脂、硅胶、反相硅胶、Sephadex LH-20凝胶等色谱法分离化合物,经质谱、核磁等光谱学方法鉴定化合物结构。结果从川牛膝乙醇提取物的大孔树脂洗脱部分中分离得到5个化合物。结论其结构鉴定为:化合物(1)杯苋甾酮;化合物(2)24-羟基杯苋甾酮;化合物(3)森告甾酮;化合物(4)苯基-β-D-吡喃葡萄糖苷;化合物(5)(+)-莱昂树脂醇-3α-O-β-D-吡喃葡萄糖苷,其中化合物5是首次从该植物中被发现。
Objective To determine the chemical constituents of Cyathula officinalis Kuan..Methods The chemical constituents were isolated and repeatedly purified by column chromatography with macroporous resin,silica gel,RP-C18,Sephadex LH-20 and identified by MS and NMR.Results We obtained 5 compounds.Conclusion The compounds were cyasterone（1）,24-hydroxycyasterone（2）,Sengosterone（3）,Phenyl β-D-glucopyranoside（4）,and（＋）-Lyoniresinol-3α-O-β-Dglucopyranoside（5）.Conclusion Compound 5 has been obtained from this plant for the first time.
出处
《中南药学》
CAS
2013年第7期495-497,共3页
Central South Pharmacy
关键词
川牛膝
苋科
化学成分
结构鉴定
Cyathula officinalis Kuan.
amaranthaceae.
chemical constituent
structural identification
