中药联合甲氨蝶呤治疗未破裂型异位妊娠临床研究

Clinical study on traditional Chinese medicine combined with methotrexate for treatment of unruptured ectopic pregnancy

目的:探讨中药联合甲氨蝶呤治疗未破裂型异位妊娠的临床疗效。方法:将90例未破裂型异位妊娠患者随机分成中药联合甲氨蝶呤的治疗组和单用甲氨蝶呤的对照组。结果:治疗组治疗有效率为95.2%,对照组为79.6%,两组差异有统计学意义(P<0.05);血β-HCG值、盆腔包块完全吸收的时间、腹痛两组差异有统计学意义(P<0.05)。结论:甲氨蝶呤与中药活血化瘀方联合使用,有杀胚迅速、加快血β-HCG的下降,减少异位妊娠包块缩小时间、减轻临床腹痛症状,是一种比较理想的保守治疗异位妊娠的方法。

Objective： To explore the clinical efficacy of traditional Chinese medicine combined with methotrexate for treatment of unruptured ectopic pregnancy.Methods： Ninety patients with unruptured ectopic pregnancy were randomly divided into traditional Chinese medicine combined with methotrexate group（combined therapy group） and simple methotrexate group（control group）.Results： The effective rates in combined therapy group and control group were 95.2% and 79.6%,respectively,there was statistically significant difference between the two groups（P 0.05）;there were statistically significant differences in blood β-human chorionic gonadotropin（β-HCG） level,complete absorption time of pelvic masses and the incidence rate of abdominal pain between the two groups（P 0.05）.Conclusion： Traditional Chinese medicine combined with methotrexate has the advantages of taking effect rapidly,fastening decrease of blood β HCG level,reducing the absorption time of pelvic masses and relieving abdominal pain in clinic,which is an ideal method for treat ectopic pregnancy.