成都市188例妇女维生素B12水平调查研究

Research on the Vitamin B12 Levels of 188 Pregnant Women in Chengdu

目的:了解妇女孕期维生素B12水平及其影响因素。方法:2011-10～2012-11将首次来院就诊的188位孕妇(孕8+4～24+1周)作为调查对象,采用调查问卷进行调查,并抽静脉血测定维生素B12水平。结果:57.45%的孕妇是计划妊娠,25.53%进行了孕前保健,50%孕前未服用叶酸,孕妇的维生素B12水平6.38%高于参考界值范围(315±174),49.45%低于参考界值范围(315±174),孕妇维生素B12水平与计划怀孕、合理膳食及营养指导有一定相关性,差异有统计学意义;与年龄、学历、收入、孕次、孕前保健及孕前服用叶酸无统计学意义。结论:成都市围孕期妇女孕前保健参与率低,孕前及孕早期合理膳食和营养指导对降低出生缺陷和不良妊娠结局意义重大。

Objective： To examine the vitamin B12 levels of pregnant women and the influencing factors.Methods： From October 2011 to November 2012,we carried out the research by choosing at random 188 pregnant women who came to our hospital for the first time.The main research methods included questionnaire and venous blood tests.Results： 57.45% of the research targets are intended pregnant,25.53% accept preconception care and 50% do not take folate before pregnancy.Among the pregnant women,the vitamin B12 level of 6.38% is higher than reference range（315 ± 174） while that level of 49.45% is lower.The vitamin B12 levels of pregnant women correlate with intended pregnancy,rational diet and nutrition guidance.Different levels have statistical significance.The levels have little statistical significance with age,education background,income,times of gestation,preconception care and taking folate before pregnancy.Conclusions： The participation rate of Chengdu＇s pregnant women in preconception care is very low.Rational diet and nutrition guidance before and during pregnancy are of great importance for reduction of birth defect.