运动皮质电刺激治疗神经病理性疼痛的研究进展

Research progress of motor cortex stimulation in the treatment of neuropathic pain

背景神经病理性疼痛表现为慢性、顽固性疼痛，发病机制仍不十分清楚。临床疗效不佳，探讨新的治疗神经病理性疼痛的方法，越来越受到更多临床医生的关注。目前神经病理性疼痛运动皮质刺激motor cortex stimulation，MCS）的临床应用和研究较多。目的探讨慢性、顽固性神经病理性疼痛安全、有效的非药物治疗方法。内容总结分析近20年来国外MCS临床应用及研究有关文献。探讨其方法、可能的治疗机制及研究进展，对MCS临床疗效及优、缺点进行分析。趋向MCS是临床上治疗慢性、顽固性神经病理性疼痛较为理想的方法，但还存在一些问题，应进行更多研究、不断改进及完善。

Background Neuropathic pain is manifested as chronic, intractable pain, and the pathogenesis is not very clear yet. The poor clinical efficacy of the commonly used treatments in neuropathic pain led to the exploration of new treatment methods by clinicians, At present, motor cortex stimulation （MCS） for neuropathic pain control has been increasingly used and investigated. Objective To explore a safe, effective, non-drug and new method for the treatment of chronic, intractable neuropathic pain. Content We summarized MCS-related foreign literatures in clinical application and research in the past 20 years, explored the methods and possible therapeutic mechanisms and progresses, and analyzed the clinical efficacy, the advantages, and disadvantages of MCS. Trend MCS is an ideal method for clinical treatment of chronic, intractable neuropathic pain, but there are still some oroblems durinu the treatment. More researches are needed to imnrove the method.