鼻咽癌常规放疗和调强放疗致皮肤损伤的对比分析

Nasopharyngeal carcinoma conventional radiotherapy and intensity-modulated radiotherapy skin injury clinical analysis

目的：对比分析鼻咽癌采用常规放疗和调强放疗在皮肤损伤发生等级的差异。方法 ：将47例鼻咽癌患者,随机分为常规放疗组23例、调强放疗组24例,鼻咽剂量均为DT 66-70 Gy。观察比较两组放射性皮肤损伤的发生率。结果：常规放疗和调强放疗组1、2、3级皮肤损伤的发生率分别为43.5%（10/23）、34.8%（8/23）、21.7%（5/23）和29.2%（7/24）、20.8%（5/24）、50.0%（12/24）,两组均未出现0级和4级病例,两组比较3级皮肤损伤差异有统计学意义（P〈0.05）。结论：鼻咽癌调强放疗3级皮肤损伤发生率明显高于常规放疗。

Objective： A comparative analysis of the nasopharyngeal carcinoma using conventional radiotherapy and intensity-modulated radiotherapy in skin injury happened levels of study.Methods： 47 cases of nasopharyngeal carcinoma patients,randomly divided into conventional radiotherapy group of 23 cases,intensity-modulated radiotherapy group of 24 cases.Nasopharyngeal dose are DT 66-70 Gy.Observation compared between the two groups radioactive skin injury incidence.Results：The conventional radiotherapy and intensity-modulated radiotherapy group 1,2,3 level skin injury incidence was 43.5%（10/23）,34.8%（8/23）,21.7%（5/23） and 29.2%（7/24）,20.8%（5/24）,50.0%（12/24）,two groups of all did not appear grade 0 level and grade 4 cases,two groups of comparisons,grade 3 skin injury has statistical significance（P0.05）.Conclusion： Intensity-modulated radiotherapy of nasopharyngeal carcinoma grade 3 skin injury incidence rate is obviously higher than that of the conventional radiotherapy.