康复新雾化吸入防治鼻咽癌放射相关口腔黏膜损伤的时机

Opportunity choice of therapeutic effects of Kangfuxing fluid spray inhalation in the radiotherapy of na-sopharyngeal carcinoma related mucous membrane of mouth

目的探讨康复新原液雾化吸入在防治鼻咽癌放射性黏膜损伤的参与时机。方法选取本院2009年5月至2012年5月收治的60例放疗期间接受康复新雾化吸入的鼻咽癌患者的临床资料进行分析。60例病例有23例康复新原液雾化吸入参与时间为放疗0次,19例为放疗10次、18例为放疗15次,康复新雾化吸入应用方法10ml/次,3次/d。结果康复新雾化吸入放疗0次、10次参与放射性口腔黏膜炎症显著轻于放疗15次参与,放疗0次、放疗10次参与对防治放射性口腔黏膜炎症无差异。结论康复新原液雾化吸入在防治放射相关口腔黏膜损伤的最佳参与时间为放疗10次,放射相关口腔黏膜炎症轻,放疗耐受性好,过早参与不能明显减轻炎症,且增加患者花费及心理负担,过晚参与放射相关口腔黏膜损伤程度重,放疗耐受性差,甚至导致放疗中断。

Objective To explore the opportunity choice of therapeutic effects of Kangfuxing Fluid spray inhalation in the radiotherapy of nasopharyngeal carcinoma related mucous membrane of mouth. Methods Clinical data of 60 cases of nasopharyngeal carcinoma received radiotherapy and Kangfuxing Fluid spray inha-lation,from May 2009 to May 2012,were collected and analysed retrospectively. Among which,23 case were re-ceived Kangfuxing Fluid spray inhalation at the beginning of radiotherapy,19 case received at the 10th of radio-therapy,18 case at the 15th. Application method of Kangfuxing Fluid spray inhalation： 10 ml one time,3 times a day. Results Therapeutic effects of Kangfuxing Fluid spray inhalation of the case received Kangfuxing Fluid spray inhalation at the beginning and the 10th were significantly better than the case at the 15th,but the case re-ceived Kangfuxing Fluid spray inhalation at the beginning and the 10th have not statistically significant differ-ence. Conculsion The best opportunity choice of therapeutic effects of Kangfuxing Fluid spray inhalation is at the 10th of nasopharyngeal carcinoma radiotherapy.