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48例传染性单核细胞增多症患儿EB病毒核酸定量和异型淋巴细胞的实验室临床意义 被引量:4

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摘要 目的研究传染性单核细胞增多症(以下简称传单)患儿实验室检测中EB病毒DNA和异型淋巴细胞的辅助诊断的临床意义。方法采取实时荧光PCR技术来定量检测EB病毒DNA的含量拷贝数(>1.0×103为阳性)和血液室异型淋巴细胞计数检测比例(>4%为阳性)。结果在48例传单患者中,EB病毒DNA>1.0×103(阳性)40例,EB病毒DNA<1.0×103(阴性)8例。异型淋巴细胞>4%(阳性)22例,异型淋巴细胞<4%(阴性)26例。EB病毒DNA阳性率占83.3%;异型淋巴细胞阳性率占45.8%。说明实验室检测对传单患儿有较高的辅助诊断价值。结论 EB病毒DNA定量拷贝数检测有相当高的诊断价值,为临床提供传单患者的快速诊断;异型淋巴细胞检测具有45.8%阳性辅助诊断价值,虽然辅助诊断价值没有核酸检测高,但是对实验室条件要求不高,更适合不具备条件开展分子生物实验室的基层医院开展辅助诊断传单患者。
作者 陈德林 潘丽
出处 《中国实用医药》 2013年第18期144-145,共2页 China Practical Medicine
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