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泰特对阿霉素所致大鼠心肌损伤的保护作用 被引量：2

Protective effects of TAD on myocardial injury caused by ADM in rats
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摘要 目的探讨泰特对阿霉素所致大鼠心肌损伤的保护作用。方法用阿霉素复制动物心肌损伤模型，泰特作为心脏保护剂，观察泰特对阿霉素所致大鼠心肌损伤的保护效果。结果通过光镜电镜形态学观察，泰特保护组心肌损伤程度明显轻于阿霉素损伤组。结论泰特对阿霉素所致大鼠心肌损伤有明显的保护作用；本文为泰特在临床应用提供了理论依据。 Objective To study the protection of TAD to myocardial injury of rats caused by ADM. Methods An animal model of myocardial injury caused by ADM was made, then,TAD was used as a protective factor. Results The degree of myocardial injury of TAD protective group was obviously lighter than ADM group. Conclusion TAD has obvious protective effects on myocardial injury caused by AMD in rats, so this study supplied a theoretic basis for clinical use of TAD.
作者 刘秀丽 张伟辉
机构地区 哈尔滨医科大学附属第一医院X-刀放疗化疗综合病房 普外科一病房
出处 《哈尔滨医科大学学报》 CAS 2000年第4期264-265,F004,共3页 Journal of Harbin Medical University
关键词 泰特 阿霉素心肌保护 大鼠 心肌损伤 TAD ADM myocardial protection rat
分类号 R542.2 [医药卫生—心血管疾病] R979.1 [医药卫生—药品]
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共引文献25

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哈尔滨医科大学学报
2000年 第4期

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