涤痰化瘀汤早期干预急性脑卒中对患者生存质量的影响

Effect of Early Treatment of Ditanhuayu Decoction on Patients with Acute Stroke and Subsequent ADL

目的观察中药涤痰化瘀汤早期干预急性脑卒中对患者生存质量的影响。方法将102例急性脑卒中患者随机分为干预组62例及对照组40例。两组均给予常规治疗,干预组在常规治疗基础上早期加用涤痰化瘀汤,疗程分为干预2周组及1月组。采用日常生活活动能力(ADL)Barthel指数(BI)评价患者发病3 d内、2周、1个月及3个月时日常生活能力。结果发病2周、1个月及3个月各随访时点,中药干预组均较对照组BI评分有所改善,而干预1个月组在3个月时恢复程度更明显(P<0.05或0.01)。结论涤痰化瘀汤早期干预可明显提高急性脑卒中患者日常生活能力,改善预后;且随干预时间延长,疗效更佳。

Objective：To observe the effect of early treatment by Ditanhuayu Decoction on patients with acute stroke and subsequent activity of daily living（ADL）.Methods：102 patients were randomly divided into two groups.62 people into treatment group of Ditanhuayu Decoction and the rest into control group.Both groups were given routine western treatment.In treatment group,patients were divided into two-weeks group and one-month group.ADL was assessed by Barthel Index（BI） within 3 days after admission as well as 2 weeks,1 month and 3 months after onset of stroke.Results：Within all follow-up points,early treatment groups improved the BI scores better than the control group（P0.01）,wherein,at 3 months follow-up the BI score of 1-month treatment group was the best（P0.01）.Conclusion：Early treatment of Ditanhuayu Decoction can obviously improve activities of daily living of stroke patients and the effect will be better with the extension of treating time.