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草药并不总是有益的Ⅱ:中药广防己和关木通的肾毒性不容忽视 被引量:5

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摘要 1994年,比利时公开披露了某一减肥组织的妇女因服用一种由芬氟拉明(食欲抑制剂)、药鼠李皮、颠茄提取物、乙酰唑胺(利尿剂)和中药汉防己、厚朴等组成的复方减肥制剂,导致33人罹患肾病的不幸事件(Am JKidney Dis,1994,24(2):172)。经查,乃是该药制造者误将中药广防己替代汉防己用于处方所致。广防己含有马兜铃酸(aristolochicacid)。
作者 希雨
出处 《国外医药(植物药分册)》 2000年第5期201-202,共2页
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同被引文献30

  • 1尚明英,李军,胡波,杨珊,李长龄,郑俊华.中药关木通中总马兜铃酸的含量测定[J].中草药,2000,31(12):899-900. 被引量:30
  • 2张卫华.三种木通利尿作用及其毒性的比较研究[J].中国药学杂志,1989,24(10):594-596. 被引量:46
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  • 7Schutte H R, Orban U, Mothes K. Biosynthesis of aristolochic acid[J]. EurJ Biochem, 1967, 1: 70.
  • 8Facchini P J, Huber-Allanach K L, Tari L W. Plant aromatic L-amino acid decarboxylase: evolution, biochemistry, regulation and metabolic engineering application [J]. Phytochemistry, 2000, 54: 121.
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