摘要
本文探讨针刺对早老性痴呆 (AlzheimerDisease,AD)大鼠中枢胆碱能神经系统的影响 ,并且分析其发挥作用的方式或途径。将动物分为正常对照组、AD组及AD针刺组 ,分别观察针刺前后动物行为学的改变 ,并经六胺银染色观察额叶皮质及海马区老年斑 (SPs)及神经原纤维缠结(NFT)的变化。结果针刺组大鼠的行为学有良性改变 ,SPs有所减少 ,而NFT的变化不明显。提示针刺对AD大鼠的中枢胆碱能神经系统有良性的调整作用。
To explore the effect of acupuncture on cholinergic central nervous system in rat of Alzheimer disease as well as the way how to create the effect. Methods: Divided rats into three groups of the normal group, AD group and the acupuncture group. Observed respectively the behavior alteration of rats before and after acupuncture, and observed the change of senile plaques (SPs) and neurofibrillary tangles (NFT) in cerebral cortex and hippocampus by special staining for SPs. Results: The rats of acupuncture group were found the behavior had better improvement and the SPs number was decreased, but NFT hadn't evidently changed. Conclusion: Acupuncture can improve rat's function of cholinergic central nervous system.
出处
《针刺研究》
CAS
CSCD
2000年第3期175-178,共4页
Acupuncture Research
