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人类白细胞抗原DR在脑卒中后免疫抑制中的作用 被引量：4

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摘要 单核巨噬细胞表面表达的人类白细胞抗原DR(human leucocyte antigen-DR,HLA-DR)是外源性抗原肽递呈过程中最重要的分子,其表达水平可在疾病早期反映外周免疫状态。HLA-DR由人类白细胞抗原基因Ⅱ类DR区域编码,主要表达于单核巨噬细胞、树突状细胞等抗原递呈细胞,在机体免疫系统中发挥着许多重要功能。近年来发现,急性脑卒中后外周单核细胞HLA-DR表达与机体免疫抑制密切相关,作者就HLA-DR在脑卒中后免疫抑制中的作用做一综述。
作者 时蒙蒙 闫福岭
机构地区 东南大学附属中大医院神经内科
出处 《东南大学学报（医学版）》 CAS 2013年第4期487-491,共5页 Journal of Southeast University(Medical Science Edition)
基金 国家自然科学基金资助项目(81271336)
关键词 人类白细胞抗原DR 卒中 免疫抑制 文献综述
分类号 R743.3 [医药卫生—神经病学与精神病学] R392.32 [医药卫生—免疫学]
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参考文献29

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二级参考文献45

共引文献6

同被引文献47

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引证文献4

二级引证文献10

东南大学学报（医学版）
2013年 第4期

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