摘要
以对硝基甲苯为原料经还原、磺化两步反应合成 4 B酸。通过正交试验确定最佳工艺条件为磺化温度 1 75℃ ,硫酸与对甲苯胺的摩尔比为 1 .1∶ 1 ,活性炭用量 3g,分出反应生成的水。在优化条件下 ,磺化收率达到93.7% ,4 B酸的总收率达到 83.3% ,产品纯度为 98%。产品经元素分析。
B acid was synthesized with pNitrotoluene as raw materials by reduction and sulfonation. The optimum reaction conditions were sulfofication temperature 175 ℃, mol ratio of sulfuric acid to ptoluidine 1.1∶1, the amount of active carbon 3 g, the water produced in the reaction process need to be separated. Under the optimum conditions, the yield of sulfofication was 93.7%, The total yield and purity of 4B acid can reach 83.3%, 98.0% respectively. The constitution and purity were confirmed by element analysis and HPLC detection.
出处
《精细石油化工》
CAS
CSCD
北大核心
2000年第6期50-52,共3页
Speciality Petrochemicals
基金
安徽省教委自然科学基金资助项目
