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血管活性肠肽瘤1例 被引量:1

Pancreatic vasoactive intestinal polypeptidesecreting tumor:A case report
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摘要 血管活性肠肽瘤(vasoactive-intestinal polypeptidesecreting tumors,VIPomas)是罕见的胰腺内分泌肿瘤.临床上以大量水样腹泻,顽固性低血钾,胃酸缺乏为主要特征性表现.此病非常罕见,临床上较易误诊.本文报道血管活性肠肽瘤1例,通过病史及实验室、影像学、内镜学、组织学检查结合相关文献进行分析讨论,提高对该病的认识. Vasoactive intestinal polypeptide-secreting tu- mor (VIPoma) of the pancreas is a rare type of pancreatic endocrine neoplasm. The main clini- cal features of VIPoma include large amount of watery diarrhea, hypokalemia and achlorhydria. Due to extreme rarity of this disease, it is eas- ily misdiagnosed. Here we report such a case to raise the awareness of this clinical entity. We also performed a review of the literature to sum- marize its clinical manifestations, diagnosis and treatment.
出处 《世界华人消化杂志》 CAS 北大核心 2013年第21期2117-2120,共4页 World Chinese Journal of Digestology
基金 贵州省科技厅社会攻关计划基金资助项目 No.SY[2010]3085~~
关键词 血管活性肠肽瘤 水样腹泻 低钾血症 诊断 VIPoma, Watery diarrhea Hypokale-mia Diagnosis
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  • 1Peng SY, Li JT, Liu YB, Fang HQ, Wu YL, Peng CH, Wang XB, Qian HR. Diagnosis and treatment of VIPoma in China: (case report and 31 cases review) diagnosis and treatment of VIPoma. Pancreas 2004; 28:93-97 [PMID: 147077371.
  • 2Ghaferi AA, Chojnacki KA, Long WE), Cameron JL, Yeo CJ. Pancreatic VIPomas: subject review and one institutional experience. J Gastrointest Surg 2008; 12: 382-393 [PMID: 17510774].
  • 3Zhang L, Lohse CM, Dao LN, Smyrk TC. Proposed histopathologic grading system derived from a study of KIT and CK19 expression in pancreatic endocrine neoplasm. Hum Pathol 2011; 42:324-331 [PMID: 21190722 IX)I: 10.1016/j.humpath.2010.09.002].
  • 4ROsch T, Lightdale CJ, Botet JF, Boyce GA, Sivak MV, Yasuda K, Heyder N, Palazzo L, Dancygier H, Schusdziarra V. Localization of pancreatic en- docrine tumors by endoscopic ultrasonography. N Engl 1 IVied 1992; 326:1721-1726 [PMID: 1317506].

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