摘要
目的:ⅢA型前列腺炎的病机特点为"湿热、膀胱气化不利、瘀浊阻滞",本研究评价气化逐瘀法联合抗生素治疗ⅢA型前列腺炎的临床疗效。方法:采用随机对照临床试验研究方法,将符合ⅢA型前列腺炎诊断的患者随机分为A、B、C 3组,3组均给予口服司帕沙星,B组同时口服坦索罗辛,C组给予司帕沙星+中药汤剂。疗程均为4周。主要疗效指标为中医证候总评分和慢性前列腺炎NIH-CPSI总评分,次要指标为前列腺液(EPS)中白细胞计数。结果:治疗后中医证候总评分B组(42.15±10.29)分和C组(41.26±11.25)分、NIH-CPSI总评分[B组(13.25±6.04)分、C组(12.38±7.19)分]较A组[(49.43±11.09)分、(17.62±5.84)分]明显降低(P均<0.05),且C组中医证候总评分治疗前后的差值(12.65±11.76)较B组(8.55±10.15)更显著(P<0.05);C组治疗后EPS白细胞计数较A组和B组明显降低(P<0.05)。结论:气化逐瘀法联合抗生素治疗ⅢA型前列腺炎有较好的疗效,值得临床推广运用。
Objective: To evaluate the clinical efficacy of bladder gasification and stasis dispersion combined with antibiotic therapy in the treatment of IIIA chronic prostatitis. Methods: We conducted a randomized controlled clinical study on 120 IliA prostatitis patients that all met the diagnostic criteria. We divided the patients into groups A, B and C of equal number to receive oral medication of spadloxacin, sparfloxacin 4- tamsulosin, and sparfloxacin + herbal decoction, respectively, all for a course of 4 weeks. We evaluated the primary therapeutic indexes according to the total scores of the patients on traditional Chinese medicine (TCM) syndrome and NIH-CPSI and the secondary therapeutic indexes based on the count of white blood cells (WBC) in the expressed prostatic secretion (EPS). Results: After treatment, the total scores on TCM syndrome and NIH-CPSI were significantly reduced in groups B (42.15 ± 10.29 and 13.25 ±6.04) and C (41.26 ± 11.25 and 12.38 ±7.19) than in A (49.43 ± 11.09 and 17.62 ±5.84) ( P 〈 0.05), and so was the WBC count in EPS in group C (7.76 ± 15.73) than in groups A (11.45 ±10.33 ) and B (12.28 ± 13.81 ) (P 〈0.05). The difference between pre- and post-treatment scores on TCM syndrome was more significant in group C (12.65 ± 11.76) than in B ( 8.55 ±10. 15 ) ( P 〈 0.05 ). Conclusion : Bladder gasification and stasis dispersion combined with antibiotic therapy is effective for the treatment of m A chronic prostatitis, and therefore deserves wide clinical application.
出处
《中华男科学杂志》
CAS
CSCD
2013年第8期732-735,共4页
National Journal of Andrology
关键词
气化逐瘀法
慢性前列腺炎
中医药治疗
疗效评价
bladder gasification and stasis dispersion
chronic prostatitis
traditional Chinese medicine
effect evaluation