溶胶-凝胶法制备不同形态的半透明羟基磷灰石陶瓷

Fabrication of Translucent Hydroxyapatite Ceramics with Different Forms by Sol-Gel Method

为探索制备不同形态半透明羟基磷灰石(T-HA)陶瓷的方法,采用微米级HA粉体为原料,甲壳素为粘结剂,用溶胶–凝胶法制备出球状和纤维状的陶瓷初坯,然后进行常压烧结得到纯HA陶瓷,最后经过热等静压烧结得到T-HA陶瓷。溶胶–凝胶法赋形简单,制备出的球状T-HA陶瓷的球形度良好,纤维状T-HA陶瓷的纵横比高,其致密度为99.1%,平均晶粒尺寸为2.2μm。其中球状半透明HA陶瓷的抗压强度为10.2 MPa,高于常规烧结得到的球状致密和多孔HA陶瓷(分别为8.9和4.7 MPa)。仿生矿化和细胞培养的结果显示半透明HA陶瓷具有良好的生物相容性。

In order to fabricate translucent hydroxyapatite ceramics with different forms, using micro-sized HA powders as the raw material and chitin as adhesive, the ceramic green was prepared by Sol-Gel method. Subse- quently, pure HA ceramics were obtained by normal pressure sintering. Translucent HA ceramics were then fabri- cated via hot isostatic pressing （HIP） sintering. The Sol-Gel method is easy to obtain shaped ceramic products. The so-produced HA ceramic spheres with a good sphericity and the HA ceramic fibers with a high aspect ratio have the density of 99.1% and the average grain size of 2.2 Ixm. Compressive strength of translucent HA ceramic spheres is 10.2 MPa whith It is higher than that of conventionally-sintered dense and porous HA ceramic spheres （8.9 and 4.7 MPa, respectively）. Results of biomimetic mineralization and cell culture show that translucent HA ceramics have good biocompatibility.