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特发性正常压力脑积水的诊断研究进展 被引量:9

Recent advance in diagnosis of idiopathic normal pressure hydrocephalus
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摘要 特发性正常压力脑积水(idiopathic normal pressure hydrocephalus,iNPH)是1965年最先提出的一种以步态异常、痴呆和尿失禁(又称Hakim三联征)为特征的交通性脑积水综合征.挪威流行病学调查估计iNPH在人群中的发病率为5.5/10万人口,患病率为21.9/10万人口[1].日本的研究表明iNPH主要发生于老年人,65岁以上患病率为1.4%~2.9%[2-3],被认为是痴呆的第一位可治性病因,脑脊液分流术可使半数以上患者症状改善[4-5].因iNPH的临床和影像学表现与其它疾病相似,早期诊断比较困难,但早期干预可获得好的疗效.随着研究深入,一些新的诊断依据不断发现,本文就有关研究进展做一综述.
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2013年第8期860-862,共3页 Chinese Journal of Neuromedicine
关键词 脑积水 步态异常 神经影像 诊断 Hydrocephalus Gait disturbance Neuroimaging Diagnosis
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参考文献24

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二级参考文献41

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共引文献96

同被引文献118

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