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肿瘤坏死因子α拮抗剂所致皮肤不良反应及对策 被引量：2

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摘要 肿瘤坏死因子α（TNF—α）是一种重要的细胞因子，在很多炎症性疾病中发挥重要作用。TNF-α拮抗剂作为生物制剂，近年来越来越多地用于类风湿关节炎、强直性脊柱炎、克罗恩病、银屑病性关节炎、银屑病等疾病的治疗中。
作者 李志量 冯素英
机构地区 中国医学科学院北京协和医学院皮肤病研究所
出处 《中华皮肤科杂志》 CAS CSCD 北大核心 2013年第8期610-613,共4页 Chinese Journal of Dermatology
关键词 TNF-α拮抗剂 肿瘤坏死因子Α 皮肤不良反应 银屑病性关节炎 炎症性疾病 类风湿关节炎 强直性脊柱炎 细胞因子
分类号 R9 [医药卫生—药学]
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参考文献34

  • 1童强,徐霞,孔瑞娜,庞亚飞,吉连梅,张菊,张兰玲,戴生明,管剑龙,韩星海,赵东宝,蔡青.肿瘤坏死因子-α拮抗剂治疗中国汉族人群强直性脊柱炎369例不良反应初步研究[J].中华风湿病学杂志,2011,15(11):785-788. 被引量：7
  • 2Lee LY, Sanderson JD, Irving PM. Anti-infliximab antibodies in inflammatory bowel disease: prevalence, infusion reactions, immunosuppression and response, a meta-analysis. Eur J Gastroenterol Hepatol, 2012, 24(9): 1078-1085.
  • 3Wee JS, Petrof G, Jackson K, et al. Infliximab for the treatment of psoriasis in the U.K.: 9 years" experience of infusion reactions at a single centre. Br J Dermatol, 2012, 167(2): 411-416.
  • 4Kerbleski JF, Gottlieb AB.Dermatological complications and safety of anti-TNF treatments. Gut, 2009, 58(8): 1033-1039.
  • 5Moustou AE, Matekovits A, Dessinioti C, et al. Cutaneous side effects of anti-tumor necrosis factor biologic therapy: a clinical review. J Am Acad Dermatol, 2009, 61(3): 486-504.
  • 6邵长庚,李新宇.抗肿瘤坏死因子α制剂在临床应用中的不良反应[J].中华皮肤科杂志,2004,37(1):1-2. 被引量：3
  • 7Papadavid E, Makris M, Dalamaga M, et al. Recall injection-site reactions to etanercept in a patient with psoriasis. Clin Exp Dermatol, 2009, 34(3): 414-415.
  • 8Bavbek S, Aydln O, Ataman S, et al. Injection-site reaction to etanercept: role of skin test in the diagnosis of such reaction and successful desensitization. Allergy, 2011, 66(9): 1256-1257.
  • 9Ko JM, Gottlieb AB, Kerbleski JF. Induction and exacerbation of psoriasis with TNF-bloekade therapy: a review and analysis of 127 cases. J Dermatolog Treat, 2009, 20(2): 100-108.
  • 10Harrison M J, Dixon WG, Watson KD, et al. Rates of new-onset psoriasis in patients with rheumatoid arthritis receiving anti- tumour necrosis factor alpha therapy: results from the British Society for Rheumatology Biologics Register. Ann Rheum Dis, 2009, 68(2): 209-215.

二级参考文献30

  • 1施桂英.肿瘤坏死因子-α抑制剂诱发银屑病[J].药物不良反应杂志,2007,9(2):103-105. 被引量：3
  • 2Aikaterini-Evaggelia M,Matekovits A,Dessinioti C,et al.Cutaneous side effects of anti-tumor necrosis factor biologic therapy:a clinical review.J Am Acad Dermatol,2009,61:486-504.
  • 3Borras-Blasco J,Navarro-Ruiz A,Borras C,et al.Adverse cutaneous reactions induced by TNF-α antagonist therapy.Southern Med J,2009,102:1133-1140.
  • 4Collamer AN,Guerrero KT,Henning JS,et al.Psoriatic skin lesions induced by tumor necrosis factor antagonist therapy:a literature review and potential mechanisms of action.Arthritis Rheum,2008,59:996-1001.
  • 5Wollina U,Hansel G,Koch A,et al.Tumor necrosis factor-alpha inhibitor-induced psoriasis or psoriasiform exanthemata:first 120 cases from the literature including a series of six new patients.Am J Clin Dermatol,2008,9:1-14.
  • 6Ko JM,Gottlieb AB,Kerbleski.JF.Induction and exacerbation of psorlasis with TNF-blockade therapy:a review and analysis of 127 cases.Dermatol Treat,2009,20:100-108.
  • 7Mohan N,Edwards ET,Cupps TR,et al.Leucocytoclastic vasculitis associated with tumor necrosis factor-alpha blocking agents.J Rheumatol,2004,319:1955-1958.
  • 8Ramos-Casals M,Brito-Zeron P,Munoz S,et al.Autoimmune diseases induced by TNF-targeted therapies:analysis of 233 cases.Medicine(Baltimore),2007,86:242-245.
  • 9Deng A,Harvey V,Sina B,et al.Interstitial granulomatous dermatitis associated with the use of tumor necrosis factor alpha inhibitors.Arch Dermatol,2006,142:198-202.
  • 10Voulgari PV,Markatseli TE,Exarchou SA,et al.Granuloma annulare induced by anti-tumor necrosis factor therapy.Ann Rheum Dis,2008,67:567-570.

共引文献8

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二级引证文献4

中华皮肤科杂志
2013年 第8期

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