摘要
The best protocol of perioperative beta-blockers remains uncertain.Previous studies have demonstrated that tight heart rate control by beta-blockers reduced perioperative myocardial ischemia and improved clinical outcomes.However,the recent studies have failed to provide evidence to support perioperative beta blockers,with potential increased mortality as showed in the POISE trial.In this paper,perioperative use of beta-blockers will be discussed,especially about the evolution of their perioperative therapeutic application and current status.
The best protocol of perioperative beta-blockers remains uncertain. Previous studies have demonstrated that tight heart rate control by beta-blockers reduced perioperative myocardial ischemia and improved clinical outcomes. However, the recent studies have failed to provide evidence to support perioperative beta blockers, with potential increased mortality as showed in the POISE trial. In this paper, perioperative use of beta-blockers will be discussed, especially about the evolution of their perioperative therapeutic application and current status. [ Keywor d s ] cardiovascular disease; noncardiac surgery; beta-blockers
出处
《医学争鸣》
CAS
北大核心
2013年第4期36-41,共6页
Negative
关键词
摘要
编辑部
编辑工作
读者
cardiovascular disease
noncardiac surgery
beta-blockers
