中西医结合治疗冠心病伴血脂异常的疗效和安全性分析

Assessment of the effects and clinical safety in the treatment of coronary heart disease with combination of Chinese tradiational and western medicine

目的探讨中西医结合治疗冠心病（CHD）伴血脂异常的疗效和安全性。方法回顾性分析我院2012年3月～2013年3月收治的冠心病患者68例，根据治疗方法分成中药组36例和对照组32例。两组均给予一般对症治疗，中药组加用复元活血汤加减治疗，对照组加用通心络胶囊，比较治疗后两组总体临床疗效及安全性，及血清甘油三酯（TG）、血清总胆固醇（TC）、低密度脂蛋白（LDL—C）、高密度脂蛋白（HDL—C）变化，并比较其不良反应发生情况。结果中药组与对照组临床总有效率分别为88．9％（32／36），71．9％（23／32），TG、TC、LDL—C水平比较，差异均有统计学意义（均P〈0．05）。两组仅出现轻微胃肠道不良反应。结论中西医联合治疗CHD可以提高临床有效率，降低血脂水平，且安全性较好。

Objective To explore the effects and clinical safety in the treatment of coronary heart disease with combination of Chinese tradiational and western medicine. Methods 68 CHD cases from March 2012 to March 2013 were analyzed retrospectively and divided into traditional Chinese medicine group（36 cases）and control group（32 cases） according to the treatment method.All the cases were given general symptomatic treatment. On this basis, traditional Chinese medicine group was given Fuyuan Huoxue tang and the control group was given Tongxinluo capsule. The clinical curative effect,serum triglyceride（TG）, Serum total cholesterol （TC）, low density lipoprotein （LDL- C）, high density lipoprotein （HDL-C） and safety were compared after treatment. Results The clinical total effective rate of treatment group and control group were88.9%（32/36） and71.9%（23/32）. The level of TG, TC and LDL-C comparison （P 〈 0.05） in two groups after treatment. Gastrointestinal adverse reaction in two groups was slight. Conclusion Combination of Chinese tradiational and western medicine in the treatment of CHD have curative effect,can reduce blood lipid levels effectively and have better security.