不稳定型心绞痛的临床观察与治疗

Clinical observation and treatment of unstable angina

目的研究不同治疗方案治疗不稳定型心绞痛的临床疗效。方法回顾性分析2009年3月～2012年3月我院接诊的90例患者的临床资料，根据治疗方法不同分为A、B组和对照组三组，每组各30例。对照组采用常规的不稳定型心绞痛患者的治疗手段对患者进行治疗，A、B组在对照组治疗的基础上分别采用小剂量和大剂量的阿托伐他汀对患者进行治疗，治疗后，对三组患者治疗前后血脂水平和炎症状况进行比较分析。结果B组患者治疗后的TC、TG、LDL、CRP的水平明显低于A组和对照组，B组患者的HDL水平明显高于A组和对照组。三组比较差异有统计学意义（P〈0．05）。B组治疗的临床总有效率（86．7％）明显高于A组（66．7％）和对照组（53-3％），三组比较差异有统计学意义（P〈0．05）。结论采用大剂量的阿托伐他汀对不稳定型心绞痛的治疗效果良好，可显著改善患者的血脂水平和炎症状况，提高治疗的总有效率。

Objective To study the clinical effects of the different treatment regimens treatment for unstable angina. Methods 90 patients with unstable angina from March 2009 to March 2012 were retrospectively analysed.According to the different treatment methods,they were divided into A,B group and control group three groups.30 patients in each group.A,B groups were used low-dose and high-dose atorvastatin treatment for patients,the control group were used conventional treatment for patients,after treatment the lipid levels and inflammatory condition of three groups were compared. Results After treatment,TC,TG,LDL,CRP levels of the patients in group B were significantly lower than group A and the control group,The HDL levels of B group were significantly higher than group A and the control group. Three groups was statistically significant （P ~ 0.0$）.The clinical total efficiency （86.7%） of group B was significantly higher than group A （66.7%） and the control group （53.3%）,three groups were statistically significant （P 〈 0.05）. Conclusion The treatment effect of use of large doses of atorvastatin in unstable angina is good,can significantly improve the patient＇s lipid levels and inflammatory conditions,improve the total efficiency of treatment.