药物复律治疗小儿阵发性室上性心动过速

Clinical efficacy of drug cardioversion in children with paroxysmal supraventricular tachycardia

目的:观察比较静脉药物治疗小儿阵发性室上性心动过速(PSVT)的临床疗效、复律时间及不良反应情况,以便指导临床用药。方法:回顾性分析62例阵发性室上性心动过速患儿使用心律平、西地兰、ATP及胺碘酮四种药物复律情况。结果:心律平转复率为75.9%,西地兰转复率为66.7%,ATP转复率为69.2%,胺碘酮转复率为75%,四种药物复律效果差异无统计学意义。结论:几种抗心律失常药物特点及适应证不同,根据患儿病情选择合适的药物有助于复律成功。

Objective： To observe the clinical effects of intravenous drug cardioversion for children with paroxysmal supraventricular tachycardia（PSVT）,and compare the time and side effects for the clinical medication guidelines.Methods： The clinical effects were retrospectively examined in 62 children with PSVT undergone cardioversion with propafenone,cedilanid,ATP and amiodarone.Results： Successful cardioversion achieved in propafenone group by 75.9%,cedilanid by 66.7%,ATP by 69.2% and amiodarone by 75%,suggested no significant difference among the four groups.Conclusion： The four antiarrhythmics have specific nature and indications in use for cardioversion in children in compliance with their conditions.