多层螺旋CT灌注成像技术在肝硬化中的应用价值

THE APPLICATING VALUE OF HEPATIC PERFUSION WITH MULTI-SLICE SPIRAL CT IN THE DIAGNOSIS OF LIVER CIRRHOSIS

目的探讨多层螺旋CT灌注成像技术在肝硬化中的诊断价值。方法运用Philips Brilliance 6螺旋CT的灌注成像技术和后处理软件,研究25例正常人与32例肝硬化患者的CT灌注成像信息。结果试验组与正常组比较:动脉的达峰时间和峰值差异不大;门静脉达峰时间延迟,峰值变化不大;肝脏组织达峰时间延迟,峰值减低;脾脏脏组织达峰时间延迟,峰值减低。试验组较对照组的血流量减低,血容量减少,平均通过时间明显减慢。结论多层螺旋CT灌注成像技术不仅能提供肝硬化时的形态学信息,还能提供肝血流动力学改变的信息,可作为肝硬化患者的常规检查。

Objective To research the value of hepatic perfusion with multi - slice spiral CT in the diagnosis of liver cirrho-sis. Methods Using Philips Brilliance 6 spiral CT and post - processing software to study 25 cases normal person CT perfusion ima-ging data and 32 cases patients with cirrhosis. Results Compared with the control group,TTP of hepatic artery has no difference, in portal vein,liver tissue and spleen tissue were delayed, and the peak of TIP were reduced in Liver and spleen. BF were reduced, BV were reduction, MTT were significantly slowed down. Conclusion Multi - slice spiral CT perfusion imaging technology not only pro- vides the morphology of cirrhosis information, but also provide hepatic hemedynamic changes. CT perfusion technology can be used as a routine examination in patients with liver cirrhosis.