踝臂指数与冠状动脉粥样硬化及其危险因素的关系

Relationship of Ankle-brachial Index with Coronary Atherosclerosis and the Risk Factors

【目的】探讨踝臂指数（ABI）与冠状动脉粥样硬化及其危险因素的相关性。【方法】对136例行冠状动脉造影的患者，收集患者的年龄、性别、体质量指数、吸烟史、既往病史等资料，并行ABI测量及生化检查，对数据进行统计学处理，分析其间及其与冠状动脉狭窄程度的相关性。【结果】双支病变组和多支病变组的ABI显著低于对照组（P〈0．05）；ABI与年龄、吸烟量、糖尿病等危险因素存在明显相关性（P〈0．01，P〈0．05）；反映冠脉病变狭窄程度的Gensini积分与ABI之间存在显著负相关（r=-0．3557，P〈0．01）。【结论】ABI与冠状动脉硬化的相关危险因素密切相关，并对冠状动脉病变狭窄程度具有较好的预测价值。

[Objective] To explore the relationship of ankle-brachial index（ABI） with coronary atheroscle- rosis and the risk factors. [Methods] Totally 136 patients underwent coronary angiography. The data such as the age, gender, body mass index（BMI）, smoking history and past history of patients were collected. ABI was measured and biochemical parameters were examined. All the data were analyzed through a statistical process. The correlation between ABI and coronary artery stenosis was analyzed. [Results] ABI in double-ves- sel disease group and multi-vessel disease group was significantly lower than that in control group（ P〈0.05）. ABI was obviously correlated with the risk factors such as age, smoking and diabetes mellitus（ P 〈0.01, P 〈 0.05）. Gensini score reflecting the degree of coronary artery stenosis was negatively correlated with ABI sig- nificantly（r= -0. 3557, P 〈0.01）. [Conclusion] ABI is closely associated with the risk factors related to cor- onary atherosclerosis, and has good value for predicting the severity of coronary artery stenosis.